Health
Reem Hospital Successfully Completes Its Inaugural Alzheimer’s Disease Clinical Trial
Abu Dhabi, Jan 05, 2026 – Reem Hospital today announced the successful completion and database lock for its clinical trial, the TauRx TRx-237-805 study, a major investigation into the novel therapy Hydromethylthionine Mesylate (HMTM) for the management of Alzheimer’s Disease, the most common form of dementia worldwide.
The trial was conducted in collaboration with Insights Research Organization & Solutions (IROS), a leading UAE-based contract research organization (CRO) and part of the M42 group, which oversaw the trial’s end-to-end management. The study also leveraged advanced diagnostic tools to identify early biomarkers of cognitive decline in individuals with a high genetic risk of developing Alzheimer’s disease.
The completion of this trial marks a major institutional milestone for Reem Hospital, establishing its capacity to contribute to global medical research and innovation. The trials’ objective was to assess the safety and tolerability of the drug, particularly within the local Emirati population.
Dr. Amir Abdelghaffar, Consultant Neurologist,head of department and Principal Investigator of the study at Reem Hospital, commented on the achievement: “Successfully locking the database for the TRx-237-805 study is a direct testament to the perseverance and scientific excellence of the entire research team. The oral drug HMTM has been investigated for safety and tolerability. This journey, investigating this novel drug was rigorous and demanding. While the clinical findings will speak for themselves, this milestone confirms our ability to conduct high-quality, audit-validated research, bringing hope and advanced therapeutic options closer to our patients and the wider community.”
The trial’s success was further validated by a recent external audit by the sponsor, which was passed successfully, a clear reflection of the research team’s commitment to the highest standards of Good Clinical Practice (GCP).
Islam ElTantawy, General Manager of IROS, said: “This collaboration reinforces the UAE’s position as a leading hub for pioneering clinical research and innovation. Conducting these trials in Abu Dhabi, in partnership with institutions such as Reem Hospital, reflects our shared commitment to advancing scientific discovery and addressing some of the most pressing health challenges of our time.”
Chairman Zaid Al Siksek added: “The successful completion of our first-ever clinical trial is a transformative moment for Reem Hospital and for healthcare in the region. This achievement, focused on the critical area of Alzheimer’s research, firmly establishes Reem Hospital as a dedicated hub for global medical innovation. It reflects our deep commitment to enhancing patient care not just through treatment, but through contributing meaningfully to international scientific discovery.”
The successful completion of the TRx-237-805 study is the result of the collaborative and sustained efforts of the entire research team.
About Reem Hospital:
Reem Hospital stands as a beacon of advanced healthcare on Reem Island in Abu Dhabi, with a capacity of 200+ beds. The hospital is a fit-for-purpose, multi-specialty healthcare facility focused on delivering the best service in line with international best practices. Reem Hospital provides innovative, value-based healthcare covering outpatient, inpatient, and post-acute care services, supported by state-of-the-art diagnostic equipment. By onboarding best-in-class doctors and integrating advanced technologies and AI tracking systems, Reem Hospital aims to provide access to world-class healthcare services in Abu Dhabi.
For more information please visit: Reem Hospital – Multi-specialty Hospital and Medical Center in Abu Dhabi, UAE
About IROS
IROS, part of the M42 group, a global tech-enabled health powerhouse, is a leading UAE-based Clinical Research Organization (CRO) dedicated to advancing excellence in clinical research and real-world evidence. Its mission is to leverage cutting-edge technologies to innovate in health and drive breakthroughs in clinical research. By conducting high-quality research and achieving groundbreaking insights, IROS aims to improve patients’ lives and shape the health landscape.
IROS’ comprehensive offerings spans all therapeutic domains, positioning it as a leader in regional medical research. With a team of high-caliber experts committed to precision, IROS offers both full-service solutions and tailored services to meet the unique needs of its partners. The organization continually integrates the latest technologies and techniques to drive innovation and excellence.
For more information, please visit: https://iros.ai/
About M42
M42 is a global health champion powered by artificial intelligence (AI), technology and genomics to advance innovation in health for people and the planet. Headquartered in Abu Dhabi, M42 combines its specialized, state-of-the-art facilities with integrated health solutions like genomics and biobanks, and harnesses advanced technologies to deliver precise, preventive and predictive care, to impactfully disrupt traditional healthcare models and positively impact lives globally.
Established in 2023, following the coming together of G42 Healthcare and Mubadala Health, M42 has more than 480 facilities in 26 countries and over 20,000 employees. M42 includes renowned healthcare providers including Cleveland Clinic Abu Dhabi, Danat Al Emarat, Diaverum, Imperial College London Diabetes Centre, Sheikh Sultan bin Zayed Hospital, and Moorfields Eye Hospital Abu Dhabi. As well as operating the Emirati Genome Programme, M42 runs Abu Dhabi BioBank and Abu Dhabi Health Data Services (ADHDS), a global tech-enabled healthcare company operating Malaffi.
Health
Safe Blood Donation Before, During, and After Ramadan – Medical Guidelines by Dr. Ganesh Dhanuka
By Dr. Ganesh Dhanuka
Specialist Internal Medicine and Nephrology
International Modern Hospital
Blood donation remains one of the most impactful humanitarian acts, capable of saving multiple lives with a single unit of blood. However, during the holy month of Ramadan, many individuals question whether it is safe to donate while fasting and how to properly prepare for donation.
From a medical standpoint, blood donation is generally safe for healthy individuals. Nevertheless, appropriate preparation — especially in the context of fasting — is essential to minimize risks such as dizziness, dehydration, or hypotension.
This article outlines evidence-based recommendations for blood donation before, during, and after Ramadan, along with its physiological, psychological, and societal benefits.
Preparing for Blood Donation Before Ramadan
Proper preparation significantly reduces the risk of adverse effects during donation. Individuals planning to donate should:
Nutritional Preparation
Consume a balanced meal rich in iron and protein approximately 2–3 hours before donating. Iron-rich foods such as lean red meat, spinach, lentils, beans, and fortified cereals help maintain adequate hemoglobin levels. Protein supports plasma volume and recovery.
Avoid donating on an empty stomach, as this increases the likelihood of lightheadedness and vasovagal reactions.
Hydration Status
Adequate hydration is critical. Donors should:
- Increase water intake the day before donation.
- Drink extra fluids on the day of donation.
Proper hydration helps maintain blood pressure and reduces the risk of fainting.
Sleep and Lifestyle Factors
- Ensure 6–8 hours of quality sleep the night before.
- Avoid alcohol for at least 24 hours prior to donation.
- Refrain from strenuous physical activity before donation.
Medical Disclosure
Bring valid identification and honestly disclose:
- Any chronic medical conditions.
- Current medications.
- Recent illnesses or procedures.
Transparency ensures donor safety and protects recipients.
What to Expect During Blood Donation
The blood donation process is generally straightforward and takes about 10–15 minutes for the actual collection.
During donation:
- Stay calm and breathe normally.
- Avoid sudden movements.
- Inform medical staff immediately if you experience dizziness, nausea, sweating, blurred vision, or weakness.
- Follow all staff instructions carefully.
Most temporary reactions, when they occur, are mild and resolve quickly with rest and hydration.
Post-Donation Care and Recovery
The post-donation period is crucial for safe recovery.
Immediate Aftercare
- Rest at the donation center for 10–15 minutes.
- Accept fluids and light refreshments provided.
- Avoid standing up abruptly.
The Next 24 Hours
- Increase fluid intake significantly.
- Consume iron-rich foods to replenish red blood cell production.
- Avoid heavy lifting for 24 hours.
- Avoid strenuous exercise on the same day.
- Avoid alcohol for several hours after donation.
If dizziness occurs, lie down and elevate your legs until symptoms resolve.
Food
Foods That Look Healthy for Weight Loss (But Actually Aren’t)
By Dr. Yara Husein (Food and Nutrition Expert)
Companies often use specific buzzwords on food labels to market products as healthy and weight-loss friendly options. In reality, these options can sometimes have the opposite effect. Here are some common foods and drinks that might be holding you back:
Fat-free dairy products
Many think that fat-free dairy products are ideal for dieting and do not contribute to weight gain. However, in truth, these products can cause weight gain because fat-free products are less satiating than their full-fat counterparts; fat is a nutrient that supports feelings of fullness and makes food more enjoyable. Furthermore, food manufacturers often replace fat with sugar in low-fat and fat-free products to compensate for the lost flavour. Beyond that, skimmed dairy products provide the body with fewer nutrients than full-fat products, because vitamins such as A, D, E, and K are fat-soluble vitamins that require fat to enter the body, be absorbed, and be utilized.
Gluten-free foods
While it is essential for people with gluten-related disorders to avoid gluten, gluten-free foods are not necessarily healthier than foods containing gluten. Some processed gluten-free foods and desserts contain the same amount of calories and added sugar—if not more—as other snacks. Studies, including a study published in the journal PeerJ, indicate that gluten-free snack foods tend to be lower in protein, fiber, and certain vitamins and minerals compared to their gluten-containing counterparts. They are also generally more expensive.
Breakfast cereals
Many people think that breakfast cereals are an ideal and healthy breakfast to start their day, but in reality, many cereals are made from refined grains that lack nutrients like protein and fiber, and they can contain a high percentage of added sugar. For example, Honey Nut Cheerios, which are marketed as heart-healthy, contain 12 grams of added sugar per cup. Eating large quantities of these and other cereals high in added sugar may lead to an increased risk of heart disease, high blood pressure, high triglyceride levels, and weight gain.
Energy and sports drinks
Companies market sports and energy drinks as ways to boost energy and athletic performance, but these drinks can contain a massive amount of sugar. Consequently, they can contribute to weight gain for people who consume them without performing intense physical exercise. For instance, a popular energy drink like Monster (473 ml) contains 54 grams of added sugar—a quantity much higher than the amount recommended by the American Heart Association (25g for women and 36g for men). Research, including a study published in the journal Pediatric Obesity, has linked the consumption of sweetened beverages to health problems, including high blood pressure, fatty liver, and obesity in children and adolescents.
Diet soda
When following a diet, many people may turn to sugar-free or calorie-free drinks, thinking they contribute to weight loss. However, studies indicate that diet soda may contribute to certain health problems by altering brain responses to food and increasing the desire to eat high-calorie foods such as sweets and fast food. A study published in the journal Nutrients linked the consumption of these drinks to a higher risk of metabolic syndrome, which is a group of symptoms that include increased belly fat, blood sugar, blood pressure, and blood lipid levels.
Health
Excessive Screen Time in Children: Digital Eye Strain, Myopia Risk, and Long-Term Vision Health
By Dr. Tahere Rezaei
Ophthalmologist
International Modern Hospital Dubai
In today’s digital era, children are spending unprecedented hours on tablets, smartphones, and social media platforms. From a clinical perspective, the impact of excessive screen exposure on pediatric eye health is becoming increasingly evident.
Ophthalmology clinics are witnessing a clear rise in complaints linked directly to prolonged device use. Children often hold screens very close to their eyes and remain intensely focused for extended periods without taking breaks. This sustained near work places continuous strain on the visual system, particularly on the eye muscles responsible for focusing.
The most immediate and common consequence is digital eye strain. Symptoms typically include:
- Headaches
- Eye fatigue
- Blurred vision
- Burning sensation
- Dryness due to reduced blinking
When children concentrate on screens, their blink rate significantly decreases. Reduced blinking leads to tear film instability, which contributes to dryness and irritation. Over time, persistent strain can affect visual comfort and academic performance.
Rising Concern: Childhood Myopia
Beyond temporary discomfort, there is a more serious long-term concern — the increasing prevalence of childhood myopia (short-sightedness).
Extended near work combined with limited outdoor exposure has been strongly associated with faster progression of myopia. Natural daylight and distance viewing play a protective role in visual development. When children spend most of their time indoors focusing on close objects, the eye adapts by elongating, leading to blurred distance vision.
Early-onset myopia is not simply about needing glasses. Higher degrees of myopia later in life increase the risk of:
- Retinal detachment
- Glaucoma
- Myopic macular degeneration
- Early cataracts
Preventing rapid myopia progression during childhood is therefore critical for long-term ocular health.
Screen Use and Sleep Disruption
Another clinically observed issue is the effect of screen exposure before bedtime. Blue light emitted from digital devices can suppress melatonin production, disrupting the natural sleep cycle. Poor sleep quality affects not only overall health but also visual comfort, concentration, and cognitive performance.
Children who use screens late at night frequently report:
- Difficulty falling asleep
- Morning eye discomfort
- Increased fatigue during the day
Sleep plays a vital role in ocular surface recovery and overall neurological health.
Supporting Healthy Visual Development
For optimal eye development, children require balanced visual habits. Key preventive measures include:
- Limiting continuous screen time
- Encouraging daily outdoor activity
- Maintaining proper room lighting
- Ensuring appropriate screen distance
- Practicing scheduled visual breaks (such as the 20-20-20 rule: every 20 minutes, look at something 20 feet away for 20 seconds)
Parents play a crucial role in modeling healthy screen behavior and establishing structured digital routines.
As Dr. Tahere Rezaei emphasizes, eye health in childhood directly influences long-term vision outcomes. Early awareness, prevention, and regular eye examinations are essential to protect children from avoidable visual complications in adulthood.
Healthy eyes today mean clearer vision for life.
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